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Management of negative symptoms of schizophrenia: a review PDF Print E-mail

SARAVANA SUBBIAN and ARUN SUBRAMANIAN

Saravana Subbian, MBBS, MRCPsych, Specialist Registrar, Child and Adolescent Psychiatry, Gardener Unit, Prestwich Hospital, Manchester M25 3BL, UK; Arun Prasad Subramanian MBBS, MRCPsych, Specialist Registrar, Learning Disability Psychiatry, Muckamore Hospital, Antrim, Northern Ireland.
Negative symptoms in schizophrenia are disabling and a source of distress for patients and carers. Multi-agency approaches are necessary for the management of negative symptoms. This paper presents a review of the clinical effectiveness of current neuroleptic and non-neuroleptic treatments, searching MEDLINE, EMBASE and PSYCHINFO (1995–2005). We identified the type of study, number of patients, response rate, and duration and limitations of the research. The keywords used were: negative symptoms, chronic schizophrenia, clozapine, antidepressants, r-TMS, CBT, psychosocial treatment, atypicals.

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